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After the decarboxylation out of pyruvate, CoA binds on the ensuing 2-carbon dioxide molecule in order to create acetyl-CoA. Which substance is then used in the newest Krebs stage, where acetyl classification is completely oxidised to help you Co2, creating NADH and you may FADH2 in the process. The fresh transportation of pyruvate on the mitochondria is facilitated by the a great specific transport necessary protein located in the mitochondrial membrane layer.
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